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SUMMARY:16.3 Haematopoiesis - Blood Formation
DTSTART;TZID=America/Los_Angeles:20260407T190000
DTEND;TZID=America/Los_Angeles:20260407T200000
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DESCRIPTION: Various substances are taken in the diet (including iron and other minerals, vitamin B12, and protein) are absorbed (vitamin B12 only in the presence of an intrinsic factor secreted by the gastric mucosa), and taken to the liver. Here vitamin B12 is stored and released to the general circulation as required as a hematopoietic factor that stimulates the production of red cells (erythropoiesis) in the red bone marrow. Other factors necessary for erythropoiesis include iron and thyroid hormones. The red cells circulate for 120 days and are then broken down (probably in the spleen) to release iron for further use. Hemoglobin without iron is excreted as bile pigments via the liver. The various mechanisms responsible for producing white blood cells (except lymphocytes) in the red bone marrow are less well understood.

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STATUS:CONFIRMED
SEQUENCE:3
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