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DTSTART;TZID=America/Los_Angeles:20260501T190000
DTEND;TZID=America/Los_Angeles:20260501T200000
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DESCRIPTION: A Grignard reagent refers to an organomagnesium halide that can be reacted with a variety of carbonyl derivatives. Grignard reagents are prepared by treating an organic halide with magnesium metal, as seen in Figure 1. An ether medium is required to stabilise the organomagnesium complex.

Figure 1. General Schematic of Grignard reagent synthesis. Step 1 involves the transfer of a single electron from magnesium to the halogen, breaking the bond within the organic halide. Step 2 involves nucleophilic attack, where the organic compound forms a bond with the magnesium ion, which is ionically bonded to the halogen. (UTex 2020). The general reaction between Grignards and carbonyls involves two main steps, including: The nucleophilic pair of electrons in the C-Mg bond attack the carbonyl group, breaking the π bond between carbon and oxygen.

Figure 2. Nucleophilic Addition. (Clark 2020). The addition of an acidic solution provides a source of hydrogen ions that hydrolyze the...

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