Leptin resistance is very similar to insulin resistance, and they work hand in hand. So if you are insulin resistant, there's a very good chance that you are also leptin resistant. So if your brain has been exposed to higher levels of leptin, because you carry high levels of adipose tissue and you're overweight, eventually, because of the constant flooding of leptin in the brain, the brain becomes desensitized or deaf to the leptin signal. And because your brain is not hearing the lips and signal, even though there is leptin in the body, because you're overweight, it does not register the full signal. So you eat more before the signal finally registers. By then, you have way I've had way more calories than your basal metabolic requirement.
So it's a vicious cycle. In addition, if you're not registering that you feel Because of this blunted signal, the brain actually thinks you're starving. So an hour of eating, your brain will now trigger a hunger signal again, and you're going to be starving again. So Lipton totally sabotages our attempts at dieting. Plus, if that's not enough, remember that a lot, a low leptin level will result in a lower metabolic rate. And if the brain thinks that you're starving, it does not matter how much or how little you're actually eating, or what you weigh, the brain will be concerned with survival.
And because the brain believes you're starving, it will instruct the thyroid to low the Mater ground, the metabolic rate to conserve energy. And in fact, many perceived thyroid problems are not about the thyroid at all. They're all about leptin resistance. So leptin is all about feedback loops and doesn't know, if you're 20 kilograms overweight. If the leptin response is weak, then the perception given is starvation, eat more and conserve energy. So your hand goes up and your metabolic rate goes down.
And this is also why, if you give the body a low calorie intake for longer than six days, the leptin levels drop too quickly, and your body is going to kick into starvation mode, and the brain will immediately reduce your metabolic rate. And the kicker is, the lower your metabolic rate, the less you feel like exercising, so of course your energy levels are going to be low. You're not going to want to exercise, you're going to be hungry, because leptin is also triggering that hunger response, low leptin levels of triggering that hunger response. So you're going to be eating more and your metabolic rate is very sluggish.